Numerical evolution of matter in dynamical axisymmetric black hole spacetimes. I. Methods and tests

We have developed a numerical code to study the evolution of self-gravitating matter in dynamic black hole axisymmetric spacetimes in general relativity. The matter fields are evolved with a high-resolution shock-capturing scheme that uses the characteristic information of the general relativistic hydrodynamic equations to build up a linearized Riemann solver. The spacetime is evolved with an axisymmetric ADM code designed to evolve a wormhole in full general relativity. We discuss the numerical and algorithmic issues related to the effective coupling of the hydrodynamical and spacetime pieces of the code, as well as the numerical methods and gauge conditions we use to evolve such spacetimes. The code has been put through a series of tests that verify that it functions correctly. Particularly, we develop and describe a new set of testbed calculations and techniques designed to handle dynamically sliced, self-gravitating matter flows on black holes, and subject the code to these tests. We make some studies of the spherical and axisymmetric accretion onto a dynamic black hole, the fully dynamical evolution of imploding shells of dust with a black hole, the evolution of matter in rotating spacetimes, the gravitational radiation induced by the presence of the matter fields and the behavior of apparent horizons through the evolution.Comment: 42 pages, 20 figures, submitted to Phys Rev

Axions and their Relatives

A review of the status of axions and axion-like particles is given. Special attention is devoted to the recent results of the PVLAS collaboration, which are in conflict with the CAST data and with the astrophysical constraints. Solutions to the puzzle and the implications for new physics are discussed. The question of axion-like particles being dark matter is also addressed.Comment: Updated version of an invited talk at the Axion Training (CERN, December 2005). To appear as a Lecture Notes in Physics (Springer-Verlag), edited by B. Beltran, M. Kuster and G. Raffel

Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage

<p>Abstract</p> <p>Background</p> <p>HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-receptors, which interact primarily with the third hypervariable loop (V3 loop) of gp120. Determination of HIV-1 affinity for either the R5 or X4 co-receptor on host cells facilitates the inclusion of co-receptor antagonists as a part of patient treatment strategies. A dataset of 1193 distinct gp120 V3 loop peptide sequences (989 R5-utilizing, 204 X4-capable) is utilized to train predictive classifiers based on implementations of random forest, support vector machine, boosted decision tree, and neural network machine learning algorithms. An <it>in silico </it>mutagenesis procedure employing multibody statistical potentials, computational geometry, and threading of variant V3 sequences onto an experimental structure, is used to generate a feature vector representation for each variant whose components measure environmental perturbations at corresponding structural positions.</p> <p>Results</p> <p>Classifier performance is evaluated based on stratified 10-fold cross-validation, stratified dataset splits (2/3 training, 1/3 validation), and leave-one-out cross-validation. Best reported values of sensitivity (85%), specificity (100%), and precision (98%) for predicting X4-capable HIV-1 virus, overall accuracy (97%), Matthew's correlation coefficient (89%), balanced error rate (0.08), and ROC area (0.97) all reach critical thresholds, suggesting that the models outperform six other state-of-the-art methods and come closer to competing with phenotype assays.</p> <p>Conclusions</p> <p>The trained classifiers provide instantaneous and reliable predictions regarding HIV-1 co-receptor usage, requiring only translated V3 loop genotypes as input. Furthermore, the novelty of these computational mutagenesis based predictor attributes distinguishes the models as orthogonal and complementary to previous methods that utilize sequence, structure, and/or evolutionary information. The classifiers are available online at <url>http://proteins.gmu.edu/automute</url>.</p

Axion interpretation of the PVLAS data?

The PVLAS collaboration has recently reported the observation of a rotation of the polarization plane of light propagating through a transverse static magnetic field. Such an effect can arise from the production of a light, m_A ~ meV, pseudoscalar coupled to two photons with coupling strength g_{A\gamma} ~ 5x10^{-6} GeV^{-1}. Here, we review these experimental findings, discuss how astrophysical and helioscope bounds on this coupling can be evaded, and emphasize some experimental proposals to test the scenario.Comment: 4 pages, 1 figure, jpconf.cls, talk presented at the ninth International Conference on Topics in Astroparticle and Underground Physics, TAUP 2005, Zaragoza, Spain, September 10-14, 200

Evading the astrophysical limits on light pseudoscalars

We study the possibility of evading astrophysical bounds on light pseudoscalars. We argue that the solar bounds can be evaded if we have a sufficiently strong self coupling of the pseudoscalars. The required couplings do not conflict with any known experimental bounds. We show that it is possible to find a coupling range such that the results of the recent PVLAS experiment are not in conflict with any astrophysical bounds.Comment: 10 pages, 5 figures, minor change

Self Interacting Dark Matter in the Solar System

Weakly coupled, almost massless, spin 0 particles have been predicted by many extensions of the standard model of particle physics. Recently, the PVLAS group observed a rotation of polarization of electromagnetic waves in vacuum in the presence of transverse magnetic field. This phenomenon is best explained by the existence of a weakly coupled light pseudoscalar particle. However, the coupling required by this experiment is much larger than the conventional astrophysical limits. Here we consider a hypothetical self-interacting pseudoscalar particle which couples weakly with visible matter. Assuming that these pseudoscalars pervade the galaxy, we show that the solar limits on the pseudoscalar-photon coupling can be evaded.Comment: 17 pages, 2 figure

Latinx Children’s Push and Pull of Spanish Literacy and Translanguaging

We explored 19 Latinx children’s literacies in Spanish and translanguaging by asking, “What are Latinx children’s experiences and beliefs regarding Spanish and translanguaging reading and writing? How do tutorial staff and teacher candidates (TCs) help the youth to resist hegemonic and bracketing practices of English-only?” This study took place in a South Texas tutorial agency, where children voluntarily attended for after-school homework help. Data sources consisted of questionnaires, interviews, focus groups, hobby essays, and newsletter articles. Most children reported negative school-related language experiences and expressed dislike and unease regarding Spanish and translanguaging reading and writing, although they lived less than 10 miles from the Mexico border. However, two tutorial staff and 15 TCs provided counter narratives and modeled that Spanish and translanguaged (hybrid) reading and writing are neither wrong nor difficult. Schools’ accountability pressures and the U.S. socio-political milieu move language to the center (centripetal forces), while forces that resist normalization are centrifugal. Implications relate to how neighborhood educational centers, TCs, and classroom teachers can help subaltern youth to resist centripetal language forces